Research projects

​This study will develop, test and validate a multidimensional Food Literacy index for school children grade 6-7. The resulting instrument will be useful for assessing food literacy levels and guide food education activities.

​By linkage of several Danish disease registers, Clinical Epidemiology has established a new National Diabetes Register covering all persons diagnosed with diabetes in Denmark.

​Fewer ethnic minorities from non-Western countries attend and complete diabetes education compared with the general population. This project investigates the relationship between access to diabetes education and social relations.

​Multi-state model to map patterns of adherence to medication.

​The project will apply a multidisciplinary approach combining studies in cellular and animal models to investigate if ''cell free'' purified AD-MSCs exosome treatment can protect and regenerate ß cell.

​ASPHALT is a research project and an intervention developed in collaboration between the non-profit organisation GAME and Health Promotion Research at Steno Diabetes Center Copenhagen.

​​The ability to work is related to different health related outcomes and is an important aspect of quality of life. 

​​The gene encoding the lysosomal cysteine protease cathepsin H (CTSH) is a type 1 diabetes (T1D) candidate gene located at the susceptibility locus on chromosome 15q25.1. The project aims at understanding the roles of CTSH and other cathepsins for beta cell function and T1D risk.

​Cities Changing Diabetes (CCD) is an international programme addressing the prevention and management of type 2 diabetes in urban settings in major cities around the world, including Copenhagen, Houston, Johannesburg, Mexico City, Rome, Shanghai, Tianjin, Vancouver and Xiamen.

​The “COVID-19 & Diabetes” project brings together qualitative and quantitative research disciplines in an effort to explore the psychosocial health of people with diabetes during the COVID-19 pandemic. So far, the project has produced several scientific articles with more to come and contributed to increased awareness on a national and international level about the thoughts, behavior changes and worries experienced by people with diabetes.

​CUlturally Sensitive TOols and Methods for ethnic minorities (CUSTOM): Building bridges between theory and practice in diabetes self-management education and support.

​​A cross-sectional study describing the prevalence of diabetic neuropathy based on questionnaire data and objective measures and their association to prevalent diabetic complications including The duration of inclusion of participants in the study is estimated to be 3 years.

​​The study is based on a design-thinking approach putting the target group (people with mental illness) at the centre of problem solving and development.

We develop a core outcome set (COS) for behaviour change interventions to prevent diabetes after pregnancies (DAP) affected by gestational diabetes. The COS is expected to enhance opportunities for comparison of future studies.

​​This project strives to identify factors that affect the working life of people with diabetes as a starting point developing interventions that can improve the experience of being at work and strengthening the employment relationship among people with diabetes.

​​Deep phenotyping of the heart with advanced imaging modalities in type 2 diabetes – implications for pathophysiology and prognosis.

​​The FACE-IT research programme aims to increase quality of life and reduce the risk of type 2 diabetes among women with prior gestational diabetes and their families.

​​This project focuses on family-based obesity interventions for children and adolescents. The aim is to produce knowledge and to develop new methods (for creating family involvement) that involve the whole family in positive and constructive ways and reduce detrimental communication.

In this study, we will investigate the antidiabetic effects of the drug fenofibrate in newly onset T1D. The study is designed as a randomized, double-blinded placebo-controlled clinical trial with 58 newly diagnosed T1D patients.    

​​The impact of liraglutide on glucose tolerance and the risk of type 2 diabetes in women with previous gestational diabetes mellitus.

​​Project collects largest ever cohort for genetic study of Diabetes nephropathy in type 1 diabetes.

​Project SoL is a series of interrelated initiatives that are all based on the supersetting approach to mobilise local communities for public health and social action.

​​The project investigates the possibilities of health promoting solutions for the benefit of the target group. It is a collaboration between City of Copenhagen Municipality and Steno Diabetes Center Copenhagen and is an adjunct to the Face It project.

​An explorative investigation of needs and possible solutions to reduce the risk of type 2 diabetes. The project is an adjunct to the Face It project.

​​The promise and unknowns of HRV measurements.

​This EU project aims at preventing overweight among children and young people consolidating, providing access to and scaling up best practices from previous European school and community health promotion interventions.

​​Hypoglycaemia and cardiac arrhythmias in type 2 diabetes.

​​In this research project we aim to identify subgroups of individuals with different patterns of disease development before the onset of type 2 diabetes and diabetic complications.

​The purpose of NEED was to develop and evaluate methods for facilitating active participation and dialogue in group based patient education. As part of the project two health education models (The Balancing Person and The Health Education Juggler) and 24 dialogue tools have been developed.

​INNODIA (an innovative approach towards understanding and arresting type 1 diabetes)is an international consortium consisting of academic institutions including SDCC, clinics, patient organizations, partners and enterprises.

​​The JOM MAMA project explores the potential of pre-conception obesity prevention and health promotion among young couples in Malaysia.

​Meal-time Administration of Exenatide for Glycaemic Control in Type 1 Diabetes Cases (The MAG1C trial): a randomised, double-blinded, placebo-controlled trial.

​​​Using cross-cultural encounters as a means of health promotion among primary school students – the Move Eat Learn (MEL) project.

​​This project is based on the adipose expandability hypothesis, which states that the link between obesity and metabolic complications does not depend on the total fat mass accumulated, but depends on the remaining capacity for expansion and functioning of the adipose tissue.

​​The project seeks to identify risk metabolomic profiles for autoimmunity and type 1 diabetes. By further investigating the relationship of these metabolomic profiles with other established genetic and environmental risk factors for type 1 diabetes, we hope to contribute to the unraveling of this complex immunologic/metabolic disease and highlight potential new therapeutic targets.

​The aim of MicrobLiver is to obtain understanding of the interaction between the host and gut microbiome in humans and the role of the gut-liver axis in early stages of alcoholic and non-alcoholic fatty liver disease.

​Currently sulphonylureas are the drug of choice when treating patients with HNF1A-diabetes (also known as MODY3). However, no study have investigated combination treatment. This study will provide insight into if combination of incretin based treatment and sulphonylurea may be a good treatment option in patients with HNF1A-diabetes. This study is a glucose-clamp study, where patients will receive combinations of GLP-1, GIP and glimepiride. The effects on insulin and glucagon will be investigated.

​​This project investigates the development and implementation of health promotion activities in deprived neighbourhoods. In these areas, the residents are at increased risk of developing diabetes and other Non-Communicable Diseases (NSD’s) as inappropriate health behaviour is concentrated among socially disadvantaged groups.

​Online peer communities for persons with type 1 diabetes are increasing in Denmark as well as worldwide, and open up a virtual space through which exchange of experience, social support and connections among peers are made possible. This is especially the case with the social media platform Facebook, which is used by 73% of the Danish population.

​PERLage is the follow up study of PERL which were a randomized doubled blind placebo controlled trial with a 3 year treatment of allopurinol/placebo to investigate whether allopurinol slows early function decline in persons with type 1 diabetes and early diabetic kidney disease.

​​Family members have important roles in everyday management of diabetes. Problems and challenges are not restricted to the person with diabetes and often affect the whole family.

​​Prevalence and progression of subclinical cardiovascular disease assessed by 3D ultrasound of the carotid arteries and relation to platelet aggregation in individuals with type 2 diabetes.

​PLATON is a cross-sectional study investigating platelet aggregation, aspirin efficacy and presence of atherosclerosis in persons with type 1 diabetes and different levels of albuminuria. 

​The impact of anemia and malaria in pregnancy on the child's DNA and later health – How do we prevent non-communicable diseases across generations? 

​Prevention of type 2 diabetes and cardiovascular disease.

​PRIORITY: Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy In Type 2 diabetic patients with normoalbuminuria.

​​An Exploratory Study to Develop a framework for a supportive PROgramme Of CarE for Adult OnsEt Type 1 Diabetes – the PROCEED study.

The PULSE project was a research-based, action-oriented exhibition-development project that took place at a science centre in Copenhagen called Experimentarium.

​The REDDSTAR Project has the potential to significantly impact the management and treatment of diabetes, with relevance for clinicians, researchers in diabetes and regenerative medicine, drug/pharmaceutical companies and ultimately for the general public.

​​Effect of time-restricted eating on behaviour and metabolism in overweight individuals at high risk of type 2 diabetes.

​RHAPSODY is focused on assessing the risk of progression of pre-diabetes to overt diabetes and of rapid deterioration of type 2 diabetes (T2D). This is achieved by a multi-omics analysis of large European cohorts. The Systems Medicine group will be provided metabolomics data for over 6000 patients progressing into type 2 diabetes.

​​Rotation for Optimal Targeting of Albuminuria and Treatment Evaluation – A rotation study of different albuminuria lowering drug classes to study individual drug response in diabetes.

​​Smoke-free Vocational Schools is a research- and intervention project which aims to implement ‘smoke-free school hours’ in nine Danish vocational education and training (VET) schools  and create new knowledge on effective tobacco control interventions.

​​The gene encoding Src kinase-associated phosphoprotein 2 (SKAP2) located on Chr 7 is a type 1 diabetes (T1D) candidate gene. The project seeks to clarify if SKAP2 affects T1D risk by modulating beta cell fragility.

​Insulin pump therapy for type 1 diabetes: How to make the most of the technology?

​​A prospective observational study of the association between plasma vitamin D and the development and progression of complications in patients with diabetes associated with Steno Diabetes Center Copenhagen.

​​Optimizing metabolic control in type 1 diabetes treated with multiple daily insulin injections - Flash glucose monitoring, carbohydrate counting with automated bolus calculation, or both?

Intensive, multifactorial treatment of people with screen-detected type 2 diabetes (ADDITION-DK trial)

Understanding cardiovascular risk and disease progression among individuals with a high-risk of developing diabetes (ADDITION-PRO)

​Effect of butyrate on inflammation and albuminuria in persons with type 1 diabetes, albuminuria and intestinal inflammation - a randomized, double-blind, placebo-controlled study.

​Renal effects of treatment with Empagliflozin alone or in combination with Semaglutide in patients with type 2 diabetes and albuminuria.

​​Developing tools for community-based health promotion.

​​Can methylglyoxal predict the onset of diabetes complications?

​The Steno T1 Risk Engine  is a screening method for cardiovascular disease in people with type 1 diabetes.

​We Act – Together for Health is a development and research project including a multi-component health promoting school intervention implemented in four Danish public schools with four control schools.

​​This PhD study (2015-2018) explores work life from the perspective of people with type 1 diabetes.

​​How can we use patient-reported outcomes to promote patient centred care and psychosocial support in type 1 diabetes routine consultations?

​​A randomized, double-blind, placebo controlled, parallel, multicenter study of the effects of 12-weeks of sodium zirconium cyclosilicate (Lokelma) on albuminuria (UACR) in patients with type 2 diabetes and hyperkalemia.