Investigating the gut hormones GLP-1, GIP, PYY and Ghrelin in Children with type 1 diabetes
We are investigating gut hormone levels in association with insulin use, BMI and insulin sensitivity - primarily stimulated levels after a mixed meal tolerance test in the first year from diabetes debut, but also levels in children having had diabetes for more than 1 year.
Sub-investigator for INNODIA and DIVID intervention
INNODIA is a multi-centre observational cohort study collecting data from newly diagnosed children and adolescents with type 1 diabetes and their first-degree relatives in more than 17 countries. In this way INNODIA will study the evolution of the disease, prediction of the risk and hopefully find a cure for those already diagnosed with type 1 diabetes.
The DIVID intervention study is an international study on 96 children and adolescents aged 6-15 years and newly diagnosed with type 1 diabetes. The study is a randomized, double-blinded, placebo-controlled study that aims to describe the influence of antiviral treatment (Pleconaril and Ribavirin) on progression of disease and residual insulin secretion.
As part of INNODIA is the clinical intervention study MELD-ATG which I have also been a sub-investigator on.
Investigating gut hormone levels (GLP-1, GiP, PYY and Ghrelin) in Children - from remission to long standing Type 1 Diabetes.
Flemming Pociot, Jesper Johannesen, Joachim Størling.
Updated 3 October 2023