The ABC Flash Study

​Optimizing metabolic control in type 1 diabetes treated with multiple daily insulin injections - Flash glucose monitoring, carbohydrate counting with automated bolus calculation, or both?

We investigate the effect of FGM in patients with type 1 diabetes and sub-optimal glycaemic control, whether FGM is superior to ABC and whether there is an additive effect of using both concepts. We also evaluate cost-benefits of the different treatment modalities.

Aim

In individuals with T1D in poor metabolic control treated with MDI:

  • To compare effects of FGM with standard diabetes training (no training in structured carbohydrate counting) with standard diabetes training and four daily SMBG measurements.
  • To compare effects of training in carbohydrate counting, automatic bolus calculation and structured FGM use with effects of training in general diabetes related issues and four daily SMBG measurements.
  • To assess whether FGM use without any specific carbohydrate training can outperform training in carbohydrate counting and bolus calculation.

200 participants will be randomized to

  1. Control,
  2. Carbohydrate counting with automated bolus calculation (ABC),
  3. Flash glucose monitoring (FGM) or d) both treatment modalities and followed for 6 months. Glycaemic parameters will be compared.

Collaborators

SDCC Partners (Nordsjællands Hospital Hillerød, Rigshospitalet, Bispebjerg and Frederiksberg Hospital and Amager and Hvidovre Hospital). 


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