- Diabetic autonomic and sensimortor neuropathy. New risk markers for early signs of development of neuropathy.
- Trials of different treatment modalities to prevent or delay progression of diabetic neuropahty.
- Investigation of the association between neuropathy and complications eg. brainfunction, foot complication and heart disease.
Whitehall II study
Aim: The association between autonomic function and inflammatory markers, beta cell function and cardiovascular disease.
Partners: University City College London, Center of diabetes research, Düsseldorf university.
Aim: The reversibility of autonomic and peripheral neuropathy in type 1 diabetes patents.
Partners: NovoNordisk Foundation, Joslin Diabetes Center (USA), University Medical Center Groningen (Holland), Folkhälsan Helsinki (Finland).
Aim: The effect of metformin on peripheral and autonomic neuropathy.
Partners: dept. endocrinology. Herlev Hospital, the research unit at Hillerød Hospital.
The young study
Aim: Prevalence of neuropathy in young type 1 diabetes patients and risk factors hereto.
Partners: dept. endocrinology Herlev Hospital Heidelberg University hospital.
Metformin and neuropati
Aim: Acute effect on markers of autonomic neuropathy in type 2 diabetes patients.
Partners: Center for diabetes research Gentofte Hospital.
Diabetes and neurovascular coupling
Aim: investigating the association between autonomic dysfunction and brain function.
Partners: NEXs Copenhagen University, Aalborg University.
Diabetic neuropathy and exercise
Aim: Investigate the safety and efficacy of exercise in type 1 diabetes patients with autonomic neuropathy.
Partners: Shefield University Hospital, Dept. of research Hillerød Hospital, Steno Diabetes Center Århus.
Diabetic gastropareses and neuropathy
Aim: Investigating the association between gastropareses and signs of neuropathy in the gastrointestinal mucosa and sign of neuropathy and gastrointestinal function.
Testing the efficacy of a novel surgical treatment method for gastroparesis (G-POEM).
Partners: Center for diabetes research Gentofte Hospital, Dept. of nuclear medicine Rigshospitalet, Dept. of Surgery, Hvidovre Hospital.
Exploring novel risk markers and potential treatment targets for neuropathic pain in type 1 diabetes
Aim: To investigate pathological changes to nerve fibres in skin biopies in patients with painful neuropathy and type 1 diabetes.
Partners: Steno Diabetes Center Aarhus and Odense, Denmark. Heidelberg University Hospital.
Genetic risk factors for diabetic neuropathy in Greenland and Denmark
Aim: To investigate new genetic risk factors for diabetic neuropathy in Greenland and Denmark.
Partners: Steno Diabetes Center Aarhus. Metabolisme center, Panum, Denmark.
New refference values for cardiovascular autonomic neuropathy (CAN)
Aim: Generate new reference values for CAN based on a healthy Danish cohort.
Partners: Steno Diabetes Center Aarhus og Sealand. Lolland-Falster study group.
Aim: To study the efficacy of treatment with probiotics on diabetic nephropathy.
Partners: DSM, Copenhagen Biocare, Metabolisme Center, Panum.