1. Womens’ health and disease
I conduct research in basic pathophysiology in women who are at risk of developing type 2 diabetes because of prior gestational diabetes. I investigate if it’s possible to prevent these women from developing type 2 diabetes.
2. Children’s health and disease
I conduct research in the development of type 2 diabetes, fatty liver, overweight and the composition of gut bacteria in children in higher risk of developing type 2 diabetes due to their exposition from the mother with gestational diabetes.
1. The impact of liraglutide on glucose tolerance and the risk of type 2 diabetes in women with previous gestational diabetes mellitus.
Aim: To investigate the effect of the glucagon-like peptide-1 receptor agonist liraglutide on pathophysiological characteristics and the risk of type 2 diabetes mellitus in women with previous gestational diabetes mellitus.
Collaborators: Elisabeth R. Mathiesen and Peter Damm, Center for pregnant women with diabetes, Rigshospitalet. Jens A. Svare, Department of Gynaecology and obstetrics, Herlev Gentofte Hospital. Tine D. Clausen and Birgit Bødker, Department of Gynaecology and obstetrics, Nordsjællands Hospital. Charlotte Strandberg and Peter M. Gørtz, Department of X-ray and scanning, Herlev Gentofte Hospital. Jens Juul Holst, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Nicklas R. Jørgensen, Department of Clinical Biochemistry, Rigshospitalet Glostrup. Henning Grønbeck, Medical hepato- gastroenterologic department, Aarhus University Hospital
2. The effect of gestational diabetes mellitus in children exposed to gestational diabetes during pregnancy.
Aim: To investigate how children exposed to gestational diabetes is characterized regarding glucose metabolism, composition of gut bacteria, liver status and body composition.