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Jørgen Rungby

Professor, Chief physicia​n, Research leader, PhD, MD​

Translational Type 2-diabetes Research

Steno Diabetes Neuro Unit​​

Contact info

Mail: joergen.rungby@regionh.dk

Phone: +45 23 29 36 85 ​​

Jørgen Rungby serves as Chief Physician and Professor at the Steno Diabetes Center and the University of Copenhagen. He currently leads the Translational Type 2 Diabetes Research group. Dr. Rungby graduated as an MD in 1984, specializing in internal medicine and endocrinology. In 1990, he earned his doctorate in neuroscience. He is a former chairman of the Danish Endocrine Society and has served on national and international committees and boards in the field of endocrinology.

He has supervised more than 30 PhD students and authored or co-authored over 270 publications. His recent research has centered on the complications of metabolic diseases affecting the brain, explored through basic biological studies, human-experimental approaches, and epidemiological research. His efforts have significantly contributed to the growing focus on this area, which now features prominently at major international congresses and has garnered substantial industrial interest. This interdisciplinary work involves endocrinology, neuropsychology, imaging, epidemiology, clinical physiology, and neurology. The establishment of the Steno Diabetes Neuro Unit, comprising national and international experts, has been pivotal in advancing these collaborations.

​​​​​​​​​Research area

  • Cognitive function

  • Neurodegenerative diseases in relation​ to diabetes mellitus 

  • Brain metabolism in diabetes mellitus 

  • The epidemiology of cognitive performance and dementia in diabetes

  • Exploring the pharmacoepidemiology of dementia in diabetes, highlighting preventive potentials of GLP-1 receptor agonists (GLP-1 RA) and SGLT2 inhibitors

  • Investigating cerebral glucose metabolism in diabetes, particularly the effects of gut hormones and the neuroprotective role of GLP-1 RA in Alzheimer's disease

  • Identifying biochemical mechanisms for neuroprotection by GLP-1 RA

  • Proposing biomarkers for endothelial CNS damage

  • Discovering potential protective effects of early endogenous amyloid deposits in Alzheimer's

​Publications​

  1. Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

  2. Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial

  3. Effects of β-hydroxybutyrate on cognition in patients with type 2 diabetes

  4. Antidiabetic medication and risk of dementia in patients with type 2 diabetes: a nested case-control study​

More info about Jørgen​



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