Study Design
The study is divided into three phases:
- Needs assessment study
- A 1-year randomized clinical trial (pilot study) including 24 participants
- A 2-year randomized clinical trial including 1,500 participants
Background and Aim
Background: The increasing prevalence of type 2 diabetes places a substantial burden on the healthcare system and negatively affects patients' quality of life. Weight loss and lifestyle modifications have been shown to induce remission of type 2 diabetes; however, there is limited knowledge on how remission can best be achieved and maintained over time.
Target population: Individuals with type 2 diabetes with a diabetes duration of ≤6 years.
Objective: To investigate whether remission of type 2 diabetes can be achieved and sustained through weight loss and lifestyle modification.
Period: The study will run from 01.01.2025 to 31.12.2030.
Collaborators
Steno Diabetes Center Aarhus, Steno Diabetes Center Odense
Bispebjerg Hospital, Department of Nutrition, Exercise and Sports
University of Copenhagen, and Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.
Funding
Novo Nordisk Foundation